Fighting Cancer through Designed and Natural Products: Discovery of New LDH-A Inhibitors and Route to the Total Synthesis of Rakicidin A
The present work aimed to synthesizing new biologically active small molecules as innovative antitumor lead candidates and to the total synthesis of a natural compound with selectivity towards cancer hypoxia. In this context, a first project involved the design and synthesis of N-acylhydrazone base...
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| Format: | Doctoral Thesis |
| Language: | en |
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Alma Mater Studiorum - Università di Bologna
2016
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| Online Access: | http://amsdottorato.unibo.it/7606/ |