Transfer of Viral and Mitochondrial Nucleic Acids through Microvesicles: a Possible Mechanism of Genetic Intra-Tumor Heterogeneity in Breast Cancer
Microvesicles (MVs) are small extracellular vesicles divided in exosomes (40-100nm), shedding microvesicles (100nm–1µm), and apoptotic bodies (1-5µm). MVs contain bioactive molecules, nucleic acids and proteins and are physiologically secreted by cells in order to guarantee cell-to-cell communicatio...
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| Format: | Doctoral Thesis |
| Language: | en |
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Alma Mater Studiorum - Università di Bologna
2016
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| Online Access: | http://amsdottorato.unibo.it/7475/ |