Ruolo di interleuchina-33 sull'espressione di geni profibrotici e sull'ipertrofia dei miofibroblasti nella fibrosi intestinale
Background: Intestinal fibrosis is a serious complication of IBD, with more than a third of Crohn’s disease (CD) patients developing a fibrostenosing phenotype with formation of strictures that will require surgical intervention. Remarkably, SAMP1/YitFc (SAMP) mice, a spontaneous model of CD, develo...
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Format: | Doctoral Thesis |
Language: | it |
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Alma Mater Studiorum - Università di Bologna
2011
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Online Access: | http://amsdottorato.unibo.it/4219/ |