Rapporto tra struttura e funzione della cistatina B e dei suoi mutanti in relazione all'epilessia mioclonica progressiva di tipo 1 (EPM1)
This work shows for the first time that native CSTB polymerizes on addition of Cu2+ and DnaK (Hsp70). Cysteines are involved in the polymerization process and in particular at least one cysteine is necessary. We propose that Cu2+ interacts with the thiol group of cysteine and oxidize it. The oxidize...
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| Format: | Doctoral Thesis |
| Language: | it |
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Alma Mater Studiorum - Università di Bologna
2010
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| Online Access: | http://amsdottorato.unibo.it/2636/ |