Development of practice-oriented LC-MS/MS methods for the determination of important drugs and their application for building PK/PD concepts
In this thesis eight robust and reliable LC-MS/MS methods were developed and validated to analyze atorvastatin, clopidogrel, furosemide, itraconazole, loratadine, naproxen, nisoldipine and sunitinib in human plasma. The active metabolites 2-hydroxyatorvastatin, 4-hydroxyatorvastatin, hydroxyitracona...
| Main Author: | |
|---|---|
| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
2011
|
| Subjects: | |
| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/5844 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-70809 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-70809 https://opus.bibliothek.uni-wuerzburg.de/files/5844/Dissertation_MRodamer_FINAL.pdf |