The Role of Vav-1, Vav-2 and Lsc in NK T cell development and NK cell cytotoxicity
The hematopoietic-specific Rho-family GTP exchange factor (GEF) Vav-1 is a regulator of lymphocyte antigen receptor signaling and mediates normal maturation and activation of B and T cells. Recent findings suggest that Vav-1 also forms part of signaling pathways required for natural and antibody dep...
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| Format: | Doctoral Thesis |
| Language: | English |
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2002
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| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/302 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-3645 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-3645 https://opus.bibliothek.uni-wuerzburg.de/files/302/chan.pdf |