Intracellular self-activation of the TrkB kinase domain causes FAK phosphorylation and disrupts actin filopodia dynamics
The tropomysin receptor kinase B (TrkB), the receptor for the neurotrophin brain-derived neurotrophic factor (BDNF), plays an important role in neuronal survival, neuronal differentiation, and cellular plasticity. Conventionally, TrkB activation is induced by binding of BDNF at extracellular sites a...
| Main Author: | |
|---|---|
| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
2021
|
| Subjects: | |
| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/23382 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-233829 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-233829 https://doi.org/10.25972/OPUS-23382 https://opus.bibliothek.uni-wuerzburg.de/files/23382/Gupta_Rohini_Dissertation.pdf |
Internet
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/23382http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-233829
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-233829
https://doi.org/10.25972/OPUS-23382
https://opus.bibliothek.uni-wuerzburg.de/files/23382/Gupta_Rohini_Dissertation.pdf