Histogenesis of Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer. In approximately 80% of cases, genomic integration of the Merkel cell polyomavirus (MCPyV) is observed and overexpression of the two MCPyV T antigens (TAgs) is regarded as the main oncogenic determinant of MCPyV-positive MCC cases. Ho...
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Format: | Doctoral Thesis |
Language: | English |
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2020
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Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/19975 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-199750 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-199750 https://opus.bibliothek.uni-wuerzburg.de/files/19975/Kervarrec_Thibault_Thesis.pdf |