NF-κB/NFAT Reporter Cell Platform for Chimeric Antigen Receptor (CAR)-Library Screening

Immunotherapy with engineered T cells expressing a tumor-specific chimeric antigen receptor (CAR) is under intense preclinical and clinical investigation. This involves a rapidly increasing portfolio of novel target antigens and CAR designs that need to be tested in time- and work-intensive screenin...

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Bibliographic Details
Main Author: Rydzek, Julian
Format: Doctoral Thesis
Language:English
Published: 2019
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/17918
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-179187
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-179187
https://opus.bibliothek.uni-wuerzburg.de/files/17918/Rydzek_Julian_CAR-Library-Screening.pdf