Novel optical methods to monitor G-protein-coupled receptor activation in microtiter plates

G-protein-coupled receptors (GPCRs) regulate diverse physiological processes in the human body and represent prime targets in modern drug discovery. Engagement of different ligands to these membrane-embedded proteins evokes distinct receptor conformational rearrangements that facilitate subsequent r...

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Bibliographic Details
Main Author: Schihada, Hannes
Format: Doctoral Thesis
Language:English
Published: 2021
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/17541
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-175415
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-175415
https://doi.org/10.25972/OPUS-17541
https://opus.bibliothek.uni-wuerzburg.de/files/17541/Schihada_Hannes_GPCR_activation.pdf