The Intricate Network of Replication-dependent Interstrand Crosslink DNA Repair
The Fanconi anemia (FA) pathway is a replication-dependent DNA repair mechanism which is essential for the removal of interstrand crosslink (ICL) DNA damages in higher eukaryotes (Moldovan and D’Andrea, 2009). Malfunctions in this highly regulated repair network lead to genome instability (Deans and...
Main Author: | |
---|---|
Format: | Doctoral Thesis |
Language: | English |
Published: |
2014
|
Subjects: | |
Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/11312 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-113121 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-113121 https://opus.bibliothek.uni-wuerzburg.de/files/11312/Rohleder_Florian_ICL-Repair.pdf |