Single molecule studies of DNA lesion search and recognition strategies
The integrity of our genome is continuously endangered by DNA damaging factors. Several cellular mechanisms have evolved to recognize and remove different types of DNA lesions. Despite the wealth of information on the three-dimensional structure and the catalytic mechanism of DNA repair enzymes, the...
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Format: | Doctoral Thesis |
Language: | English |
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2014
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Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/11188 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-111886 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-111886 https://opus.bibliothek.uni-wuerzburg.de/files/11188/buechner_claudia_dnalesion.pdf |