Identification and functional characterization of TGF-β inducible, immunosuppressive miRNAs in human CD8+ T cells

Identification and functional characterization of TGF-β inducible, immunosuppressive miRNAs in human CD8+ T cells

While TGF-β is able to regulate miRNA expression in numerous cell types, TGF-β-dependent changes in the miRNA profile of CD8+ T cells had not been studied before. Considering that TGF-β suppresses CD8+ T cell effector functions in numerous ways, we wondered whether induction of immune-regulatory miR...

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Bibliographic Details
Main Author: Premachandran Nair, Anoop Chandran
Format: Doctoral Thesis
Language:English
Published: 2014
Subjects:
Transforming Growth Factor beta
Antigen CD8
miRNS
Interferon <Gamma->
Immunsystem
Regulation
ddc:570
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/10974
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-109741
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-109741
https://opus.bibliothek.uni-wuerzburg.de/files/10974/Chandran_PA_Anoop_TGF-beta-inducible_miRNAs_in_CD8_T_cells.pdf

Internet

https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/10974
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-109741
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-109741
https://opus.bibliothek.uni-wuerzburg.de/files/10974/Chandran_PA_Anoop_TGF-beta-inducible_miRNAs_in_CD8_T_cells.pdf

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