La protéine accessoire Vpu du VIH-1 inhibe l'activité antivirale des pDCs à travers un processus ILT7-dépendant

Viral protein U (Vpu) is an accessory protein of HIV‐1 that efficiently targets BST2/Tetherin, a cellular restriction factor that acts as molecular anchor impeding the release of various enveloped viruses from the cell surface. The recently discovered natural receptor of BST2 is ILT7, a molecule exc...

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Bibliographic Details
Main Author: Bérubé-Côté, Édouard
Other Authors: Cohen, Éric A.
Language:fr
Published: 2015
Subjects:
Vpu
TLR
Online Access:http://hdl.handle.net/1866/12737