Lost in Nucleocytoplasmic Transportation: New Insights Into FUS-Mediated Neurodegeneration
Nucleocytoplasmic transport (NCT) declines during aging and in the context of age-dependent neurodegenerative diseases. However, the mechanisms underlying NCT decline in the disease are poorly understood. FUS is an RNA binding protein that shuttles between the nucleus and cytoplasm and is actively i...
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Format: | Others |
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eScholarship@UMMS
2020
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Online Access: | https://escholarship.umassmed.edu/gsbs_diss/1107 https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2116&context=gsbs_diss |