Lost in Nucleocytoplasmic Transportation: New Insights Into FUS-Mediated Neurodegeneration

Nucleocytoplasmic transport (NCT) declines during aging and in the context of age-dependent neurodegenerative diseases. However, the mechanisms underlying NCT decline in the disease are poorly understood. FUS is an RNA binding protein that shuttles between the nucleus and cytoplasm and is actively i...

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Bibliographic Details
Main Author: Lin, Yen-Chen
Format: Others
Published: eScholarship@UMMS 2020
Subjects:
ALS
FUS
Online Access:https://escholarship.umassmed.edu/gsbs_diss/1107
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2116&context=gsbs_diss