Investigating the role of the c-Jun NH2-terminal kinase pathway in ErbB2-driven breast cancer and macrophage polarization

Breast cancer is the second most common malignancy in the world, accounting for over 1.7 million new diagnoses and an estimated 500,000 deaths per year (1). Overexpression of the receptor tyrosine kinase ErbB2, also known as Her2 or Neu, occurs in over 30% of breast cancers and correlates with metas...

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Bibliographic Details
Main Author: Yu, Lola
Format: Others
Published: eScholarship@UMMS 2020
Subjects:
JNK
IL6
Online Access:https://escholarship.umassmed.edu/gsbs_diss/1094
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2103&context=gsbs_diss