Cytosolic DNA sensing in autoimmune and autoinflammatory diseases
Cytosolic DNA sensing plays a key role in autoimmune and autoinflammatory diseases. STING is a cytosolic adaptor protein which upon activation leads to induction of type I interferons and inflammatory cytokines. Recently, gain-of-function mutations in STING have been identified in patients with an a...
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| Format: | Others |
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eScholarship@UMMS
2020
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| Online Access: | https://escholarship.umassmed.edu/gsbs_diss/1074 https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2086&context=gsbs_diss |