Elucidating the Roles of Novel Genes in MHC-I Presentation

The major histocompatibility complex class I (MHC-I) antigen presentation pathway is necessary for the immune system to be able to detect, control, and eliminate cancers. MHC-I binds oligopeptides derived from cellular proteins and presents them on the cell surface to CD8+ T cells. Consequently, the...

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Bibliographic Details
Main Author: Kriegsman, Barry
Format: Others
Published: eScholarship@UMMS 2019
Subjects:
MHC
Online Access:https://escholarship.umassmed.edu/gsbs_diss/1018
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2027&context=gsbs_diss