Towards Understanding the Molecular Basis of Human Endoderm Development Using CRISPR-Effector and Single-Cell Technologies
The definitive endoderm gives rise to several specialized organs, including the thymus. Improper development of the definite endoderm or its derivatives can lead to human disease; in the case of the thymus, immunodeficiency or autoimmune disorders. Human pluripotent stem cells (hPSCs) have emerged a...
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| Format: | Others |
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eScholarship@UMMS
2019
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| Online Access: | https://escholarship.umassmed.edu/gsbs_diss/1008 https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2018&context=gsbs_diss |