Understanding Nuage-mitochondrial Coupling in Drosophila piRNA Biogenesis

In the Drosophilaovary, PIWI-interacting RNAs (piRNAs) suppress transposon expression, ensuring female fertility. PIWI proteins Aub and Ago3, loaded with ping-pong piRNAs and reside in perinuclear nuage granules, engage in reciprocal transposon transcript cleavage termed the ping-pong cycle. The oth...

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Bibliographic Details
Main Author: Ge, Tianfang
Format: Others
Published: eScholarship@UMMS 2018
Subjects:
Online Access:https://escholarship.umassmed.edu/gsbs_diss/983
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1990&context=gsbs_diss