Axon Death Pathways Converge on Axed to Promote Axon Disassembly

Axons use a conserved program to actively drive their own destruction after injury. Axon degeneration is present in many neurological disorders and an axon death program could be a major pharmaceutical target to preserve neuronal function. This intrinsic signaling cascade activates pro-degenerative...

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Bibliographic Details
Main Author: Burdett, Thomas C.
Format: Others
Published: eScholarship@UMMS 2017
Subjects:
Online Access:https://escholarship.umassmed.edu/gsbs_diss/898
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1903&context=gsbs_diss