Characterization of Drug Resistance in Mycobacterium Tuberculosis via Saturating Mutagenesis of Drug Targets: A Master’s Thesis

Mycobacterium tuberculosis isolates from multiple drug resistant or extensively drug resistant patients show a particular set of mutations in drug targets conferring resistance. However, the selection of drug-resistant strains in vitro yields an alternative set of mutations, thought to result fro...

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Bibliographic Details
Main Author: Harris, Michelle J.
Format: Others
Published: eScholarship@UMMS 2012
Subjects:
Online Access:https://escholarship.umassmed.edu/gsbs_diss/605
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1608&context=gsbs_diss