The Paradigm of Self-compartmentalized M42 Aminopeptidases: Insight into Their Oligomerization, Substrate Specificities, and Physiological Function

The Paradigm of Self-compartmentalized M42 Aminopeptidases: Insight into Their Oligomerization, Substrate Specificities, and Physiological Function

M42 aminopeptidases are dinuclear enzymes widely found in prokaryotes but completely absent from eukaryotes. They have been proposed to hydrolyze peptides downstream the proteasome or other related proteolytic complexes. Their description relies mainly on the pioneering work on four M42 aminopeptida...

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Bibliographic Details
Main Author: Dutoit, Raphaël
Other Authors: Droogmans, Louis
Format: Doctoral Thesis
Language:en
Published: Universite Libre de Bruxelles 2020
Subjects:
Biochimie
Biologie moléculaire
oligomeric state transition
peptide degradation
co-catalytic metalloenzyme
MH clan
PDZ-like domain
proteolysis
morpheein
peptidasome
Online Access:https://dipot.ulb.ac.be/dspace/bitstream/2013/314337/3/Thesis_rdutoit.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/314337/4/Table_of_content_thesis_rdutoit.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/314337/5/ContratDiDutoit.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/314337

Internet

https://dipot.ulb.ac.be/dspace/bitstream/2013/314337/3/Thesis_rdutoit.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/314337/4/Table_of_content_thesis_rdutoit.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/314337/5/ContratDiDutoit.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/314337

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