Genetic and lipotoxic endoplasmic reticulum stress in pancreatic β cells: a critical process in common and rare forms of diabetes

Genetic and lipotoxic endoplasmic reticulum stress in pancreatic β cells: a critical process in common and rare forms of diabetes

ABSTRACTThe prevalence of diabetes is increasing dramatically, incurring a major health and socioeconomic burden. Type 2 diabetes (T2D), the most prevalent form of diabetes, results from a variable combination of insulin resistance and insulin deficiency, secondary to pancreatic β-cell failure. Thes...

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Bibliographic Details
Main Author: Lytrivi, Maria
Other Authors: Cnop, Miriam
Format: Doctoral Thesis
Language:en
Published: Universite Libre de Bruxelles 2020
Subjects:
Endocrinologie
Diabétologie
pancreatic islets
free fatty acids
monogenic diabetes
RNA sequencing
proteome
type 2 diabetes
lipotoxicity
dietary fat
îlots pancréatiques
acides gras libres
graisse alimentaire
Online Access:https://dipot.ulb.ac.be/dspace/bitstream/2013/305600/5/Contrat_Maria_Lytrivi.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/305600/3/TableOfContents.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/305600/4/ThesisFullText.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/305600

Internet

https://dipot.ulb.ac.be/dspace/bitstream/2013/305600/5/Contrat_Maria_Lytrivi.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/305600/3/TableOfContents.pdf
https://dipot.ulb.ac.be/dspace/bitstream/2013/305600/4/ThesisFullText.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/305600

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