A signalling function of phosphatidylinositol 3,4-bisphosphate in cell migration of breast cancer cells
SHIP2 is a phosphatase that belongs to the family of the phosphoinositide 5-phosphatases. It is known to dephosphorylate PI(3,4,5)P3 to PI(3,4)P2 imparting a tight control of the PI 3-kinase pathway. Over the last decade, SHIP2 has been described as a tumor promotor or tumor suppressor in several ca...
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| Format: | Doctoral Thesis |
| Language: | en |
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Universite Libre de Bruxelles
2018
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| Online Access: | http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/268960 |