Lipid-GPCR interactions: from activation of sphingosine-1-phosphate receptors to modulation of vasopressin V2 receptor function
GPCRs form the largest family of membrane proteins in human genome and mediate signal transmission in a wide panel of essential physiological processes, and they are thus a major source of pharmaceutical targets. Investigating GPCR interactions with their cognate ligands and their membrane environme...
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Format: | Doctoral Thesis |
Language: | en |
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Universite Libre de Bruxelles
2015
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Online Access: | http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/216727 |