Development, characterization and evaluation of crystalline nanoparticles for enhancing the solubility, the dissolution rate and the oral bioavailability of poorly water-soluble drugs
When considering oral administration, drug release from its pharmaceutical form and its dissolution into gastrointestinal fluids generally precedes absorption and systemic availability. The solubility-dissolution behaviour of a drug is frequently the rate-limiting step to absorption of drugs from th...
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| Format: | Doctoral Thesis |
| Language: | fr |
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Universite Libre de Bruxelles
2006
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| Online Access: | https://dipot.ulb.ac.be/dspace/bitstream/2013/210816/1/bdad33df-4bd2-4a2d-bc6f-b5eea1c3c5d0.txt https://dipot.ulb.ac.be/dspace/bitstream/2013/210816/4/8b7c1c0d-f8b3-49ea-8896-a9cb6f7e8eee.txt http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210816 |