Phosphatidylethanolamine regulates the function and the structure of LmrP, a bacterial multidrug transporter protein associated to antibiotic resistance

The multidrug transporter LmrP, member of the major facilitator superfamily (MFS), confers L. lactis and recombinant E. coli cells resistance to an array of cytotoxic compounds including antibiotics. LmrP mediates drug extrusion from the plasma membrane by an electrogenic proton/drug exchange reacti...

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Bibliographic Details
Main Author: Hakizimana, Pierre
Other Authors: Raussens, Vincent
Format: Doctoral Thesis
Language:fr
Published: Universite Libre de Bruxelles 2008
Subjects:
PE
Online Access:http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210486