MnSOD AND AUTOPHAGY IN PREVENTION OF OXIDATIVE MITOCHONDRIAL INJURIES INDUCED BY UVB IN MURINE SKIN
UVB radiation is a known environmental carcinogen that causes DNA damage and increase ROS generation in mitochondria. Accumulating evidence suggests that mtDNA damage and increased ROS generation trigger mitochondrial translocation of p53. Within mitochondria, p53 interacts with nucleoid macromolecu...
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Format: | Others |
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UKnowledge
2012
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Online Access: | http://uknowledge.uky.edu/toxicology_etds/2 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1001&context=toxicology_etds |