MnSOD AND AUTOPHAGY IN PREVENTION OF OXIDATIVE MITOCHONDRIAL INJURIES INDUCED BY UVB IN MURINE SKIN

UVB radiation is a known environmental carcinogen that causes DNA damage and increase ROS generation in mitochondria. Accumulating evidence suggests that mtDNA damage and increased ROS generation trigger mitochondrial translocation of p53. Within mitochondria, p53 interacts with nucleoid macromolecu...

Full description

Bibliographic Details
Main Author: Bakthavatchalu, Vasudevan
Format: Others
Published: UKnowledge 2012
Subjects:
UVB
Online Access:http://uknowledge.uky.edu/toxicology_etds/2
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1001&context=toxicology_etds