PRECLINICAL TARGETING OF TREM2 FOR THE TREATMENT OF ALZHEIMER'S DISEASE-TYPE PATHOLOGY IN A TRANSGENIC MOUSE MODEL

Alzheimer's disease (AD) is defined as a progressive neurodegenerative disorder and is characterized by a devastating mental decline. There are three pathological hallmarks of the disease necessary for its diagnosis, these are extracellular amyloid plaques comprised of the beta-amyloid (Aβ) pro...

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Bibliographic Details
Main Author: Price, Brittani Rae
Format: Others
Published: UKnowledge 2019
Subjects:
Online Access:https://uknowledge.uky.edu/physiology_etds/43
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1042&context=physiology_etds