PROTEIN KINASE A AND EPAC MEDIATE CHRONIC PAIN AFTER INJURY: PROLONGED INHIBITION BY ENDOGENOUS Y1 RECEPTORS IN DORSAL HORN

PROTEIN KINASE A AND EPAC MEDIATE CHRONIC PAIN AFTER INJURY: PROLONGED INHIBITION BY ENDOGENOUS Y1 RECEPTORS IN DORSAL HORN

Inflammation or nerve injury sensitizes several populations of nociceptive neurons in the dorsal horn of the spinal cord, including those that express the neuropeptide Y (NPY) Y1 receptor (Y1R). Our overall hypothesis is that after tissue or nerve injury, these Y1R-expressing neurons enter a state o...

Full description

Bibliographic Details
Main Author: Fu, Weisi
Format: Others
Published: UKnowledge 2016
Subjects:
NPY
Y1R
pain
AC1
PKA
Epac
Medical Neurobiology
Medical Pathology
Medical Pharmacology
Medical Physiology
Neurosciences
Online Access:https://uknowledge.uky.edu/physiology_etds/31
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1030&context=physiology_etds

Internet

https://uknowledge.uky.edu/physiology_etds/31
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1030&context=physiology_etds

Similar Items