THE CARDIAC L-TYPE CALCIUM CHANNEL DISTAL CARBOXYL- TERMINUS AUTO-INHIBITION IS REGULATED BY CALCIUM

The L-type calcium channel (LTCC) provides trigger Ca2+ for sarcoplasmic reticulum Ca2+-release and LTCC function is influenced by interacting proteins including the LTCC Distal Carboxyl-terminus (DCT) and calmodulin. DCT is proteolytically cleaved, and re-associates with the LTCC complex to regulat...

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Bibliographic Details
Main Author: Crump, Shawn M
Format: Others
Published: UKnowledge 2012
Subjects:
Online Access:http://uknowledge.uky.edu/physiology_etds/5
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1004&context=physiology_etds