UNDERSTANDING THE THERMODYNAMICS AND ORAL ABSORPTION POTENTIAL OF PHARMACEUTICAL AMORPHOUS SOLID DISPERSIONS

UNDERSTANDING THE THERMODYNAMICS AND ORAL ABSORPTION POTENTIAL OF PHARMACEUTICAL AMORPHOUS SOLID DISPERSIONS

Supersaturating drug delivery systems, such as amorphous solid dispersions (ASDs), have been used extensively to elevate the apparent solubility and oral bioavailability of poorly water-soluble drugs. However, despite the numerous examples of success in increasing solubility and oral bioavailability...

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Bibliographic Details
Main Author: Setiawan, Nico
Format: Others
Published: UKnowledge 2018
Subjects:
supersaturation
crystallization
amorphous
poorly water-soluble drugs
excipients
absorption
Chemical Engineering
Pharmacy and Pharmaceutical Sciences
Online Access:https://uknowledge.uky.edu/pharmacy_etds/85
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1090&context=pharmacy_etds

Internet

https://uknowledge.uky.edu/pharmacy_etds/85
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1090&context=pharmacy_etds

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