QUANTIFICATION OF FACTORS GOVERNING DRUG RELEASE KINETICS FROM NANOPARTICLES: A COMBINED EXPERIMENTAL AND MECHANISTIC MODELING APPROACH

QUANTIFICATION OF FACTORS GOVERNING DRUG RELEASE KINETICS FROM NANOPARTICLES: A COMBINED EXPERIMENTAL AND MECHANISTIC MODELING APPROACH

Advancements in nanoparticle drug delivery of anticancer agents require mathematical models capable of predicting in vivo formulation performance from in vitro characterization studies. Such models must identify and incorporate the physicochemical properties of the therapeutic agent and nanoparticle...

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Bibliographic Details
Main Author: Fugit, Kyle Daniel
Format: Others
Published: UKnowledge 2014
Subjects:
Drug Release Kinetics
Liposomes
Micelles
Topotecan
Doxorubicin
Lipids
Medicinal and Pharmaceutical Chemistry
Medicinal-Pharmaceutical Chemistry
Oncology
Pharmaceutical Preparations
Pharmaceutics and Drug Design
Transport Phenomena
Online Access:http://uknowledge.uky.edu/pharmacy_etds/37
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1040&context=pharmacy_etds

Internet

http://uknowledge.uky.edu/pharmacy_etds/37
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1040&context=pharmacy_etds

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