PEPTIDE DEFORMYLASE: A MODELING STUDY OF THE ACTIVE SITES OF PLANTS AND BACTERIA AND THE DESIGN, SYNTHESIS, AND BIOLOGICAL ACTIVITY ANALYSIS OF PEPTIDE-BASED INHIBITORS

All nascent polypeptides synthesized in bacteria, mitochondria, or chloroplastsstart with a N-formylmethionine. Peptide deformylase (PDF) is a mononuclear metal ionprotein that is responsible for removing the N-formyl group of nascent proteins found inbacteria and chloroplasts in order for them to b...

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Bibliographic Details
Main Author: Barnes, Jonathan C.
Format: Others
Published: UKnowledge 2006
Subjects:
Online Access:http://uknowledge.uky.edu/gradschool_theses/212
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1214&context=gradschool_theses