PEPTIDE DEFORMYLASE: A MODELING STUDY OF THE ACTIVE SITES OF PLANTS AND BACTERIA AND THE DESIGN, SYNTHESIS, AND BIOLOGICAL ACTIVITY ANALYSIS OF PEPTIDE-BASED INHIBITORS
All nascent polypeptides synthesized in bacteria, mitochondria, or chloroplastsstart with a N-formylmethionine. Peptide deformylase (PDF) is a mononuclear metal ionprotein that is responsible for removing the N-formyl group of nascent proteins found inbacteria and chloroplasts in order for them to b...
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UKnowledge
2006
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Online Access: | http://uknowledge.uky.edu/gradschool_theses/212 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1214&context=gradschool_theses |