DEVELOPMENT AND CHARACTERIZATION OF NOVEL MONOCLONAL ANTIBODIES FOR STUDYING PRION PATHOGENESIS
Monoclonal antibodies (mAbs) recognizing different regions of PrP are potential tools in the study of prion diseases and immunotherapy. We used shuffled recombinant prion protein containing elk and mouse PrP as antigen to produce monoclonal antibodies in mice. We found that mAb 5C6 mapped to a disco...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
UKnowledge
2011
|
| Subjects: | |
| Online Access: | http://uknowledge.uky.edu/gradschool_theses/95 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1095&context=gradschool_theses |