COMPUTER SIMULATION OF A HOLLOW-FIBER BIOREACTOR: HEPARAN REGULATED GROWTH FACTORS-RECEPTORS BINDING AND DISSOCIATION ANALYSIS

COMPUTER SIMULATION OF A HOLLOW-FIBER BIOREACTOR: HEPARAN REGULATED GROWTH FACTORS-RECEPTORS BINDING AND DISSOCIATION ANALYSIS

This thesis demonstrates the use of numerical simulation in predicting the behavior of proteins in a flow environment. A novel convection-diffusion-reaction computational model is first introduced to simulate fibroblast growth factor (FGF-2) binding to its receptor (FGFR) on cell surfaces and regula...

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Bibliographic Details
Main Author: Zhang, Changjiang
Format: Others
Published: UKnowledge 2011
Subjects:
Numerical simulation
laminar convection diffusion flow
mass transport
fibroblast growth factor and receptor binding
parallel computing
Biochemistry
Computer Engineering
Systems Biology
Online Access:http://uknowledge.uky.edu/gradschool_diss/816
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1819&context=gradschool_diss

Internet

http://uknowledge.uky.edu/gradschool_diss/816
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1819&context=gradschool_diss

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