EVALUATION OF THE PHYSICOCHEMICAL PROPERTIES AND STABILITY OF SOLID LIPID NANOPARTICLES DESIGNED FOR THE DELIVERY OF DEXAMETHASONE TO TUMORS

EVALUATION OF THE PHYSICOCHEMICAL PROPERTIES AND STABILITY OF SOLID LIPID NANOPARTICLES DESIGNED FOR THE DELIVERY OF DEXAMETHASONE TO TUMORS

Pre-clinical and clinical trials suggest that pre-treatment with dexamethasone (Dex) may facilitate enhanced uptake of subsequently administered chemotherapeutic agents. To reduce the side effects associated with systemic administration of Dex, solid lipid nanoparticles (SLNs) containing dexamethaso...

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Bibliographic Details
Main Author: Howard, Melissa
Format: Others
Published: UKnowledge 2011
Subjects:
solid lipid nanoparticles
crystallinity
drug loading
PEGylation
stability
Chemical Engineering
Pharmacy and Pharmaceutical Sciences
Physical Chemistry
Online Access:http://uknowledge.uky.edu/gradschool_diss/806
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1809&context=gradschool_diss

Internet

http://uknowledge.uky.edu/gradschool_diss/806
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1809&context=gradschool_diss

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