COMPUTATIONAL DESIGN OF 3-PHOSPHOINOSITIDE DEPENDENT KINASE-1 INHIBITORS AS POTENTIAL ANTI-CANCER AGENTS
Computational drug design methods have great potential in drug discovery particularly in lead identification and lead optimization. 3-Phosphoinositide dependent kinase-1 (PDK1) is a protein kinase and a well validated anti-cancer target. Inhibitors of PDK1 have the potential to be developed as anti-...
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| Format: | Others |
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UKnowledge
2009
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| Online Access: | http://uknowledge.uky.edu/gradschool_diss/757 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1760&context=gradschool_diss |