EFFECT OF COMBINATION EXPOSURE TO ZIDOVUDINE AND SULFAMETHOXAZOLE-TRIMETHOPRIM ON IMMUNE RESPONSE IN MICE AND HUMANS
The drug-drug interaction involving zidovudine and sulfamethoxazole-trimethoprim was investigated using an in vitro culture system, an in vivo mouse model, and a clinical trial in HIV-infected patients. We hypothesized that combination exposure causes immune cell populations in the bone marrow to un...
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| Format: | Others |
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UKnowledge
2005
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| Online Access: | http://uknowledge.uky.edu/gradschool_diss/411 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1414&context=gradschool_diss |