LOSS OF BLOOM SYNDROME PROTEIN CAUSES DESTABILIZATION OF GENOMIC ARCHITECTURE AND IS COMPLEMENTED BY ECTOPIC EXPRESSION OF Escherichia coli RecG IN HUMAN CELLS
Genomic instability driven by non-allelic homologous recombination (NAHR) provides a realistic mechanism that could account for the numerous chromosomal abnormalities that are hallmarks of cancer. We recently demonstrated that this type of instability could be assayed by analyzing the copy number va...
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| Format: | Others |
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UKnowledge
2011
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| Online Access: | http://uknowledge.uky.edu/gradschool_diss/201 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1204&context=gradschool_diss |