THE FUNCTION OF ERBIN, A SCAFFOLD PROTEIN, AS A TUMOR SUPPRESSOR IN COLON CANCER

THE FUNCTION OF ERBIN, A SCAFFOLD PROTEIN, AS A TUMOR SUPPRESSOR IN COLON CANCER

Erbin belongs to the LAP (leucine-rich repeat and PDZ domain) family of scaffolding proteins that play important roles in orchestrating cell signaling. Here, we show that Erbin functions as a tumor suppressor in colon cancer. Analysis of Erbin expression in patient specimens reveals that Erbin is do...

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Bibliographic Details
Main Author: Stevens, Payton D.
Format: Others
Published: UKnowledge 2018
Subjects:
Polarity
EMT
Cell Motility
ERK signaling
Scaffold protein
Tumor Suppressor
Medical Cell Biology
Medical Molecular Biology
Online Access:https://uknowledge.uky.edu/biochem_etds/36
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1036&context=biochem_etds

Internet

https://uknowledge.uky.edu/biochem_etds/36
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1036&context=biochem_etds

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