THE CELLULAR NUCLEIC ACID BINDING PROTEIN REGULATES THE ALZHEIMER’S DISEASE β-SECRETASE PROTEIN BACE1

Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the elderly population and is believed to be caused by the overproduction and accumulation of the toxic amyloid beta (Aβ) peptide in the brain. Aβ is produced by two separate enzymatic cleavage events of the larger membr...

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Bibliographic Details
Main Author: Holler, Christopher J
Format: Others
Published: UKnowledge 2012
Subjects:
Online Access:http://uknowledge.uky.edu/biochem_etds/12
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1006&context=biochem_etds