TRAF2 phosphorylation regulates CD40 signaling to facilitate B-cell lymphoma progression

TRAF2 phosphorylation regulates CD40 signaling to facilitate B-cell lymphoma progression

CD40 is a TNF-Receptor (TNFR) superfamily member that functions to promote several facets of the humoral immune response--including B cell proliferation, differentiation, antibody isotype switching, and cytokine expression. TNFR superfamily members lack intrinsic kinase activity and must recruit mem...

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Bibliographic Details
Main Author: Workman, Lauren Michelle
Other Authors: Habelhah, Hasem
Format: Others
Language:English
Published: University of Iowa 2014
Subjects:
CD40
Lymphoma
NF-kB
Phosphorylation
TRAF2
Cell Biology
Online Access:https://ir.uiowa.edu/etd/6665
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=8164&context=etd

Internet

https://ir.uiowa.edu/etd/6665
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=8164&context=etd

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