Structure and function of the disordered regions within translesion synthesis DNA polymerases
Normal DNA replication is blocked by DNA damage in the template strand. Translesion synthesis is a major pathway for overcoming these replication blocks. In this process, multiple non-classical DNA polymerases form a complex at the stalled replication fork called the mutasome. This complex is struct...
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Format: | Others |
Language: | English |
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University of Iowa
2018
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Online Access: | https://ir.uiowa.edu/etd/6625 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=8124&context=etd |