Regulation of NLRP3 inflammasome activation by mitochondria

Pattern recognition receptors coordinate innate immune responses by sensing infection or injury. Nucleotide-binding, leucine rich repeat, and pyrin domain-containing protein 3 (NLRP3) is a cytosolic PRR which perceives diverse pathogenic and sterile in...

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Bibliographic Details
Main Author: Elliott, Eric Isaac
Other Authors: Sutterwala, Fayyaz S.
Format: Others
Language:English
Published: University of Iowa 2018
Subjects:
Online Access:https://ir.uiowa.edu/etd/6099
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7794&context=etd