C3 glomerulopathy: exploring the role of the glomerular micro-environment in disease pathogenesis

C3 glomerulopathy (C3G) encompasses a group of severe renal diseases characterized by “dominant C3” deposition in the renal glomerulus. Patients typically present as nephritic nephrotics, with hematuria, hypertension, heavy proteinuria and edema. Within ten years of diagnosis, 50% of affected patien...

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Bibliographic Details
Main Author: Xiao, Xue
Other Authors: Smith, Richard J. H.
Format: Others
Language:English
Published: University of Iowa 2017
Subjects:
Online Access:https://ir.uiowa.edu/etd/6019
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7500&context=etd