Particle size distribution (PSD) equivalency using novel statistical comparators and PBPK input models

Particle size distribution (PSD) equivalency using novel statistical comparators and PBPK input models

For disperse system drug formulations, meaningful particle size distribution (PSD) comparators are essential in determining pharmaceutical equivalency and predicting biopharmaceutical equivalence in terms of the effect of particle size on the rate and extent of drug input. In formulation development...

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Bibliographic Details
Main Author: Ngeacharernkul, Pratak
Other Authors: Kirsch, Lee E.
Format: Others
Language:English
Published: University of Iowa 2017
Subjects:
Bioequivalence
Overlap metrics
Particle size distributions
PBPK
Similarity factor
Pharmacy and Pharmaceutical Sciences
Online Access:https://ir.uiowa.edu/etd/5973
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7454&context=etd

Internet

https://ir.uiowa.edu/etd/5973
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7454&context=etd

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