Regulation of the signal transduction pathways of the unfolded protein response during chronic and physiological ER stresses
The unfolded protein response (UPR) is activated by protein misfolding stress in the endoplasmic reticulum (ER). The UPR is a transcriptional program that aims to maintain ER folding capacity, where imbalances between protein load and processing ability is termed ER stress. Signal transduction of th...
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| Language: | English |
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University of Iowa
2016
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| Online Access: | https://ir.uiowa.edu/etd/5760 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=7222&context=etd |