Identification of small molecule inhibitors of regulator of G protein signaling proteins for pretherapeutic development for treatment of multiple pathologies
Regulator of G-protein Signaling (RGS) proteins temporally regulate the G protein signaling cascades initiated by GPCR activation. Reports have established dysregulation of RGS expression in a variety of disease states including several cancers. Additionally, use of genetic ablation techniques has i...
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| Format: | Others |
| Language: | English |
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University of Iowa
2017
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| Online Access: | https://ir.uiowa.edu/etd/5420 https://ir.uiowa.edu/cgi/viewcontent.cgi?article=6900&context=etd |